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Blood bank course part 1

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Blood Bank Foundations

  • Overview of blood banks

  • Blood collection, processing, and storage

  • Blood components & their clinical uses

  • Hemoglobin and its role in oxygen transport

Red Blood Cell (RBC) Structure & Function

  • Anatomy and physiology of RBCs

  • Chemistry of blood group substances

  • Analysis of how blood types are formed in the body

ABO System Deep Dive

  • H antigen and its formation

  • Role of FUT1 & FUT2 (fucosyltransferases)

  • Formation of A, B, AB, and O antigens

  • Understanding AB antibodies, antigen-antibody reactions, and immune roles

  • Bombay & Para-Bombay blood groups (rare phenotypes)

Rh System Overview

  • Discovery of ABO and Rh systems

  • Rh antigens: D, C, c, E, e

  • Rh alloimmunization and clinical significance

  • Rh nomenclature: Wiener vs. Fisher-Race

  • Genotyping, Rh dosage, and zygosity

  • Weak D, Partial D, and RHD gene deletions

  • Rare Rh types: Rh null, Rh mod, F antigen, and Cw antigen

Immunohematology Concepts

  • Antigen vs. Antibody reactions

  • Role of the immune system(All include references)

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